ProtParam for 23.5 Culicine family protein

motif search - genome.jp

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLQTIITLTV ILLPFSSSHN IPPWNGCYAV GCSTQQGCTP WNFYRYPCYR TCYYNRYCPP 

        70         80         90        100        110        120 
PSPPSKKCYK ITHVATGKSM TSSEVFNATT KAKYATVSSN PPANFLWTME PSYGGVNYIQ 

       130        140        150        160        170        180 
NANTLEFLKA DSNGTRLALN ETLDRSFQFR PIQTKEGASK LQLQSVFNNG FLFVQTLGQG 

       190        200 
GSTVQITTDP FTNYYQTIWC ITELYC 

Number of amino acids: 206

Molecular weight: 23202.35

Theoretical pI: 8.82


Amino acid composition: 
Ala (A)  10   4.9%
Arg (R)   6   2.9%
Asn (N)  15   7.3%
Asp (D)   3   1.5%
Cys (C)   9   4.4%
Gln (Q)  12   5.8%
Glu (E)   6   2.9%
Gly (G)  12   5.8%
His (H)   2   1.0%
Ile (I)  10   4.9%
Leu (L)  15   7.3%
Lys (K)   9   4.4%
Met (M)   3   1.5%
Phe (F)  11   5.3%
Pro (P)  15   7.3%
Ser (S)  17   8.3%
Thr (T)  24  11.7%
Trp (W)   4   1.9%
Tyr (Y)  14   6.8%
Val (V)   9   4.4%
Pyl (O)   0   0.0%
Sec (U)   0   0.0%

 (B)   0   0.0%
 (Z)   0   0.0%
 (X)   0   0.0%



Total number of negatively charged residues (Asp + Glu): 9
Total number of positively charged residues (Arg + Lys): 15

Atomic composition:

Carbon      C       1046
Hydrogen    H       1576
Nitrogen    N        268
Oxygen      O        307
Sulfur      S         12

Formula: C1046H1576N268O307S12
Total number of atoms: 3209

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    43360
Abs 0.1% (=1 g/l)   1.869, assuming all pairs of Cys residues form cystines


Ext. coefficient    42860
Abs 0.1% (=1 g/l)   1.847, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 43.45
This classifies the protein as unstable.



Aliphatic index: 64.85

Grand average of hydropathicity (GRAVY): -0.285